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Test Result is Negative Despite Symptoms – What to Do?

Published 2024-01-27 21:03 by Nordictest
Test Result is Negative Despite Symptoms – What to Do?

You have symptoms that suggest the disease you believe you have, but your test result was negative. What do you do now? This question will receive various answers depending on what you have been tested for. However, it is crucial to remember that several health problems can manifest similar symptoms.

For instance, you might have a severe cold that is not strep throat, and despite recognizing the symptoms, you received a negative result on your strep throat test. The first thing you should do is realize that your symptoms could be due to something else. Let's take a look at what it might be.


It is possible to be infected with chlamydia and be asymptomatic. However, when you do experience symptoms and know that you've had unprotected sex with a person who has chlamydia, you may wonder about a negative test result.

But there are other health conditions that can cause similar symptoms to chlamydia:

  • Heavy discharge – This could be due to other sexually transmitted diseases like gonorrhea, bacterial vaginosis, or fungal infections.
  • Painful urination – This is also a symptom of urinary tract infections as well as cystitis.
  • Pain during intercourse – Pain can result from vaginal dryness, endometriosis, or other pelvic conditions.
  • Testicular pain – This could be due to epididymitis, testicular torsion, or other infections.
  • Rectal pain – Rectal pain, as well as blood in the stool, can be signs of hemorrhoids, anal fissures, and other gastrointestinal issues.


Herpes is caused by the HSV virus and has symptoms that can closely resemble those of other conditions. If you receive a negative result on your herpes test, your symptoms may indicate another health problem.

Examples of symptoms and what they may suggest:

  • Blisters and sores – These can be caused by syphilis, allergic reactions, as well as skin issues like eczema and impetigo.
  • Painful urination – This could be a urinary tract infection.
  • Itching and burning sensation – This may be a fungal infection, allergic reaction, or some form of skin problem.
  • Flu-like symptoms – It could be a viral infection like a cold or the flu.
  • Swollen lymph nodes – This is a common symptom of various infections and the immune response in the body.
  • Redness and rash – This could be a fungal infection, eczema, or other skin conditions.
  • Headache and muscle aches – Muscle and headache pain is common with many viral infections and general illnesses.


The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhea. The symptoms can resemble those of several other health conditions. This is why it's essential to test for gonorrhea because the infection can be asymptomatic and only manifest symptoms later, which may be mistaken for something else.

If you have tested negative for herpes but still have symptoms, consider the following:

  • Heavy discharge – Could be chlamydia, bacterial vaginosis, or fungal infections.
  • Painful urination – Could be a urinary tract infection or chlamydia.
  • Increased urination frequency – Could be a urinary tract infection or prostate problems in men. Type 2 diabetes (insulin resistance) can also lead to increased urination.
  • Swollen testicles – May be a sign of epididymitis, testicular torsion, or another infection.
  • Rectal pain – May be an anal fissure or hemorrhoids.
  • Sore throat – Could be caused by various types of viral and bacterial infections, such as strep throat.
  • Pelvic pain or abdominal pain in women – May be another sexually transmitted disease or ovarian cysts.
  • Irregular menstruation – Could be due to hormonal imbalance, fibroids, or other gynecological issues.


Menopause is a completely natural process that occurs at the end of a woman's reproductive years. You can take a menopause test to see if the symptoms you are experiencing might be related to it. However, there are many symptoms associated with menopause that can indicate other health issues.

Here are common symptoms that may signal something else:

  • Hot flashes – Women can experience hot flashes and sweating due to thyroid problems, infections, and certain types of cancer.
  • Irregular periods – This may be due to thyroid disorders, hormonal imbalance, or fibroids.
  • Mood swings and depression – Mood swings and depression are not unique to menopause and can be related to hormonal disturbances as well as mental health issues.
  • Fatigue – Fatigue is common during menopause but can also result from sleep disturbances or anemia. Candida overgrowth can also cause fatigue, so consider the possibility of a candida test.
  • Weight gain – This may be caused by factors such as thyroid disorders, insulin resistance, and other metabolic conditions.
  • Vaginal dryness – It could be due to medication, autoimmune diseases, or Sjögren's syndrome.
  • Memory problems – Brain fog can have several causes, including stress, sleep deprivation, and neurological conditions like dementia.
  • Reduced libido – This could be due to stress, relationship problems, or other underlying health issues unrelated to menopause.
  • Joint pain – Joint pain can be related to rheumatism or autoimmune diseases.


You have clear symptoms of salmonella, but the test shows negative results. This bacterial infection is mostly associated with contaminated food or water. Since the symptoms are similar to those of other diseases, a negative test result should prompt you to consider other possibilities.

Examples of symptoms and what they may be:

  • Diarrhea – Diarrhea can result from many other gastrointestinal diseases, as well as foodborne illnesses like E. coli infections. IBS and inflammatory bowel diseases can also lead to diarrhea.
  • Fever – Fever is a common symptom of viral infections like the flu, urinary tract infections, and many other bacterial infections.
  • Abdominal cramps – This could be a symptom of appendicitis, gastroenteritis, menstrual cramps, or food intolerance.
  • Nausea and vomiting – Nausea and vomiting can occur when you consume something inappropriate, as well as with the flu. Other causes can include migraines or early pregnancy.
  • Headache – This could be due to fatigue, dehydration, viral illnesses, and more.
  • Muscle pain – Muscle pain can result from the flu and other types of infections. Additionally, physical overexertion can lead to muscle pain.
  • Blood in the stool – This may be due to hemorrhoids, inflammatory bowel disease, or cancer.
  • Fatigue – Fatigue is a non-specific symptom that can result from sleep difficulties, anemia, or possibly thyroid disorders.

What Should You Do?

If you have the symptoms mentioned above but receive a negative test result, it is essential to seek medical attention. With the correct diagnosis, you can receive a treatment plan tailored to your condition, which can hopefully lead to you feeling better soon.